Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Levofloxacin Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | ALB | P02768 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.98 |
| ▸ | TUBB | P07437 | 7/20 | 0.98 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.98 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.98 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.98 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.98 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.98 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.98 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.98 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.98 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.98 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.98 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.98 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ofloxacin SCHEMBL27542046 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL14163982 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL515263 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL24373 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL5532921 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL9745243 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Dextrofloxacine SCHEMBL4316947 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL1442676 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Levofloxacin Anhydrous SCHEMBL1442440 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Ofloxacin SCHEMBL7719091 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 50102 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| CN-122094963-A | Cardioprotective lipids and methods of use | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075390-A | Preparation and application of novel cow uterus injectant | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079294-A | Method for degrading levofloxacin in wastewater based on visible light driving CMPs photocatalytic system | — | 2026-05-26 | — | — | CN | claimed |
| CN-121754734-B | Silk fibroin-based bionic artificial tympanic membrane with gradient structure and preparation method thereof | Fuxiang Sitai medical technology (Suzhou) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122076471-A | Metal basic salt mineralized membrane, preparation method thereof and application of metal basic salt mineralized membrane serving as heterogeneous catalyst in treatment of organic wastewater | — | 2026-05-26 | — | — | CN | claimed |
| US-20260137766-A1 | LIPOSOME FORMULATIONS FOR TREATMENT OF ACTIVE TUBERCULOSIS | ARCHIVEL FARMA S L (ES) | 2026-05-21 | — | — | US | claimed |
| WO-2026106446-A1 | SELF-COOLING NANOCERAMIC ADDITIVE, METHOD OF MANUFACTURE AND USES THEREOF | NANOMATERIALES QUIMICOS AVANZADOS S.A. DE C.V. (MX) | 2026-05-21 | — | — | WO | claimed |
| WO-2026106551-A1 | ANTIMICROBIAL PEPTIDE NANONETS AND METHODS OF USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2026-05-21 | — | — | WO | claimed |
| EP-4743153-A1 | MEDICAL SYSTEMS FOR TREATING CONDITIONS AND DISEASES OF THE PATIENT'S BODY CAVITIES | UTT Urine Topical Treatment Ltd (IL) | 2026-05-20 | — | — | EP | claimed |
| EP-0423119-A1 | PROCESS AND DEVICE FOR TRANSMITTING NUMERICAL DATA. | MARCHAND RENAUD (FR) | 1991-04-24 | — | — | EP | claimed |
| EP-0149213-B1 | VECTOR PROCESSOR | HITACHI, LTD. (JP) | 1991-02-13 | — | — | EP | claimed |
| WO-1991000191-A1 | HINGE FOR SUN VIZORS FOR MOTOR VEHICLES | INDUSTRIAS TECHNO-MATIC, S.A. (ES) | 1991-01-10 | — | — | WO | claimed |
| EP-0398371-A2 | Apparatus and method for the execution control of microprogrammed machine instructions in a data processing system | Siemens Nixdorf Informationssysteme Aktiengesellschaft (DE) | 1990-11-22 | — | — | EP | claimed |
| EP-0394553-A2 | Use of fluorine containing pyridone carboxylic acid derivatives for preparing a medicament for the treatment of HIV infections | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | claimed |
| WO-1990006030-A1 | PROCESS AND DEVICE FOR TRANSMITTING NUMERICAL DATA | MARCHAND, RENAUD (FR) | 1990-05-31 | — | — | WO | claimed |
| US-4923862-A | Topical preparation containing ofloxacin | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-05-08 | — | — | US | claimed |
| EP-0256455-A1 | Fast division method for long operands in data processing equipments, and circuit therefor | SIEMENS AKTIENGESELLSCHAFT (DE) | 1988-02-24 | — | — | EP | claimed |
| EP-0206283-A2 | Optically active pyridobenzoxazine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1986-12-30 | — | — | EP | claimed |
| EP-0051154-A1 | Method and device for combining variable-length operands in data processing systems | SIEMENS AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | claimed |