Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398844 | 0.92 | STS (0.65) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL17988714 | 0.90 | STS (0.55) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL15399462 | 0.84 | STS (0.63) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL17991998 | 0.83 | MAPT (0.65) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL15398755 | 0.83 | RAB9A (0.62) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL15399312 | 0.82 | STS (0.73) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL17988704 | 0.77 | STS (0.65) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL17988700 | 0.76 | NPC1 (0.45) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL17988706 | 0.76 | MIF (0.55) | STSMAPTRAB9ANPC1KDM4E | |
| SCHEMBL17988699 | 0.75 | STS (0.49) | STSMAPTRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| US-20140005149-A1 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005149-A1 | Substituted diphenyl derivatives | DPYD, VHL, TP53 | STS 3633/4885MAPT 3367/4885RAB9A 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.