Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988699 | 0.90 | STS (0.49) | STSMAPTNPC1RAB9AALOX12 | |
| SCHEMBL17991978 | 0.88 | MAPT (0.50) | STSMAPTNPC1RAB9AALOX12 | |
| SCHEMBL15398873 | 0.84 | STS (0.66) | STSMAPTNPC1RAB9AALOX12 | |
| SCHEMBL15399710 | 0.84 | STS (0.69) | STSMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17991989 | 0.83 | MAPT (0.61) | MAPTNPC1RAB9AALOX12KIF11 | |
| SCHEMBL15398655 | 0.83 | MAPT (0.58) | STSMAPTNPC1RAB9AALOX12 | |
| SCHEMBL17991990 | 0.83 | MAPT (0.58) | STSMAPTNPC1RAB9AALOX12 | |
| SCHEMBL15398844 | 0.79 | STS (0.65) | STSMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17988698 | 0.78 | STS (0.58) | STSMAPTNPC1RAB9AALOX12 | |
| SCHEMBL17988696 | 0.77 | ALOX12 (0.47) | STSMAPTNPC1RAB9AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| US-20140005149-A1 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005149-A1 | Substituted diphenyl derivatives | DPYD, VHL, TP53 | STS 3633/4885MAPT 3367/4885NPC1 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.