Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 11/20 | 0.36 |
| ▸ | AKT2 | P31751 | 11/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15401384 | 1.00 | TAAR1 (0.39) | TAAR1AKT1AKT2TSHRKDM1A | |
| SCHEMBL15401890 | 0.76 | AKT1 (0.39) | AKT1AKT2 | |
| SCHEMBL15401891 | 0.76 | AKT1 (0.39) | AKT1AKT2 | |
| SCHEMBL2038191 | 0.74 | TAAR1 (0.34) | TAAR1KDM1ARCOR1CYP2A6 | |
| SCHEMBL991567 | 0.73 | CYP2A6 (0.42) | TAAR1KDM1ARCOR1CYP2A6 | |
| SCHEMBL15264700 | 0.72 | LPL (0.45) | — | |
| SCHEMBL15264703 | 0.72 | LPL (0.45) | — | |
| SCHEMBL12522585 | 0.72 | BACE1 (0.42) | KDM1A | |
| SCHEMBL15401995 | 0.72 | AKR1C1 (0.39) | TSHR | |
| SCHEMBL15401996 | 0.72 | AKR1C1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2868660-B1 | ANTITUMOR EFFECT POTENTIATOR COMPRISING AN IMIDAZOOXAZINE COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-9375434-B2 | Antitumor effect potentiator composed of imidazooxazine compound | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-06-28 | — | — | US | disclosed |
| CN-103459400-B | Mi Zuo Bing oxazine compounds or its salt | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2016-05-18 | — | — | CN | disclosed |
| US-9289431-B2 | — | — | 2016-03-22 | — | — | US | disclosed |
| EP-2698372-B1 | NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-20150164909-A1 | ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
| EP-2868660-A1 | ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND | Taiho Pharmaceutical Co., Ltd. (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-8772283-B2 | Imidazo-oxazine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| EP-2698372-A1 | NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2014-02-19 | — | — | EP | disclosed |
| US-20140005185-A1 | NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2014-01-02 | — | — | US | disclosed |
| CN-103459400-A | Novel imidazo-oxazine compound or salt thereof | TAIHO PHARMACEUTICAL CO LTD | 2013-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164909-A1 | ANTITUMOR EFFECT POTENTIATOR COMPOSED OF IMIDAZOOXAZINE COMPOUND | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, TPD52L2 | TAAR1 1687/4885AKT1 419/4885AKT2 620/4885 |
| US-20140005185-A1 | NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF | IKZF3, IKZF2, IKZF1 | TAAR1 1469/4885AKT1 2351/4885AKT2 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.