Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | STAT1 | P42224 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15400979 | 0.86 | NPC1 (0.58) | HIF1AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL15400503 | 0.86 | NPC1 (0.66) | TP53HIF1AKDM4EALDH1A1NPC1 | |
| SCHEMBL15400579 | 0.84 | HIF1A (0.55) | TP53HIF1AKDM4EALDH1A1NPC1 | |
| SCHEMBL15400996 | 0.84 | NPC1 (0.67) | TP53HIF1AKDM4EALDH1A1NPC1 | |
| SCHEMBL15401641 | 0.84 | SMN1; SMN2 (0.60) | TP53HIF1AKDM4EALDH1A1NPC1 | |
| SCHEMBL1243101 | 0.83 | MAPT (0.65) | TP53HIF1AKDM4EALDH1A1NPC1 | |
| SCHEMBL16771871 | 0.82 | TP53 (0.62) | TP53HIF1AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16771933 | 0.80 | ALDH1A1 (0.60) | TP53HIF1AKDM4EALDH1A1NPC1 | |
| SCHEMBL16771912 | 0.79 | TP53 (0.52) | TP53KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL16771942 | 0.78 | PSEN1 (0.60) | TP53ALDH1A1SMN1; SMN2ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603128-B | Antifungal heterocycle carbonyl acid amides | 杜邦公司 | 2017-09-08 | — | — | CN | claimed |
| EP-2867228-B1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | DU PONT (US) | 2017-07-26 | — | — | EP | claimed |
| EP-2867228-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. Du Pont de Nemours and Company (US) | 2015-05-06 | — | — | EP | claimed |
| CN-104603128-A | Fungicidal heterocyclic carboxamides | DU PONT | 2015-05-06 | — | — | CN | claimed |
| US-8815772-B2 | Fungicidal heterocyclic carboxamides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | claimed |
| WO-2014004064-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-03 | — | — | WO | claimed |
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | FMC CORPORATION | 2014-01-02 | — | — | US | claimed |
| CN-104603128-B | Antifungal heterocycle carbonyl acid amides | 杜邦公司 | 2017-09-08 | — | — | CN | disclosed |
| EP-2867228-B1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | DU PONT (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2867228-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. Du Pont de Nemours and Company (US) | 2015-05-06 | — | — | EP | disclosed |
| CN-104603128-A | Fungicidal heterocyclic carboxamides | DU PONT | 2015-05-06 | — | — | CN | disclosed |
| US-8815772-B2 | Fungicidal heterocyclic carboxamides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2014004064-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-03 | — | — | WO | disclosed |
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | FMC CORPORATION | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | CBR3, CBR1, NOX3 | TP53 4624/4885HIF1A 3419/4885KDM4E 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.