SCHEMBL15401611

SCHEMBL15401611

CNC(=O)C(O)c1ccccc1COc1cc(C)cc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 4/20 0.38
TP53 P04637 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PARP10 Q53GL7 1/20 0.37
MAOB P27338 1/20 0.37
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402063 0.90 KMT2A (0.45) SMN1; SMN2MEN1KMT2AHPGDMAOB
SCHEMBL15401831 0.90 MAOB (0.40) ALDH1A1L3MBTL1TDP1MEN1KMT2A
SCHEMBL15401828 0.88 MEN1 (0.46) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL15375495 0.87 MEN1 (0.44) ALDH1A1MAPTL3MBTL1SMN1; SMN2MEN1
SCHEMBL15401961 0.86 FFAR1 (0.39) MAPTNPSR1L3MBTL1SMN1; SMN2LMNA
SCHEMBL15401969 0.86 MAPT (0.40) ALDH1A1MAPTNPSR1L3MBTL1SMN1; SMN2
SCHEMBL15375353 0.85 FABP4 (0.47) ALDH1A1MAPTNPSR1L3MBTL1SMN1; SMN2
SCHEMBL15402296 0.85 ALDH1A1 (0.40) ALDH1A1MAPTNPSR1L3MBTL1SMN1; SMN2
SCHEMBL15375385 0.84 PARP10 (0.42) ALDH1A1MAPTNPSR1L3MBTL1SMN1; SMN2
SCHEMBL27940488 0.84 KCNH2 (0.35) MEN1KMT2AMAOBKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA ALDH1A1 1164/4885MAPT 3967/4885NPSR1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.