SCHEMBL15401682

SCHEMBL15401682

CCc1ccccc1OCc1cc(Cl)ccc1C(O)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.46
MRGPRX4 Q96LA9 2/20 0.42
PTGER1 P34995 3/20 0.41
FABP4 P15090 3/20 0.41
FABP5 Q01469 3/20 0.41
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
SGMS2 Q8NHU3 3/20 0.41
ANO1 Q5XXA6 1/20 0.40
FABP3 P05413 1/20 0.40
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402503 0.88 PTGDR2 (0.49) PTGDR2MRGPRX4PTGER1FABP4FABP5
SCHEMBL15375643 0.88 FABP4 (0.54) PTGDR2MRGPRX4PTGER1FABP4FABP5
SCHEMBL17328308 0.87 PTGDR2 (0.46) PTGDR2MRGPRX4PTGER1FABP4FABP5
SCHEMBL15401433 0.87 LPAR1 (0.45) PTGDR2MRGPRX4FABP4FABP5MEN1
SCHEMBL15402016 0.87 PTGDR2 (0.50) PTGDR2MRGPRX4PTGER1FABP4FABP5
SCHEMBL15375381 0.86 MAPT (0.45) FABP4FABP5MEN1KMT2ASGMS2
SCHEMBL15402039 0.86 GAA (0.42) MRGPRX4FABP4FABP5MEN1KMT2A
SCHEMBL17328310 0.81 FABP4 (0.44) PTGDR2MRGPRX4PTGER1FABP4FABP5
SCHEMBL15401896 0.81 PTGDR2 (0.46) PTGDR2MRGPRX4MEN1KMT2ASGMS2
SCHEMBL15375360 0.80 PTGDR2 (0.47) PTGDR2MRGPRX4PTGER1FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA PTGDR2 938/4885MRGPRX4 1236/4885PTGER1 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.