SCHEMBL15401433

SCHEMBL15401433

COC(=O)C(O)c1ccc(Cl)cc1COc1ccccc1C(C)C

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 4/20 0.45
FABP4 P15090 3/20 0.41
FABP5 Q01469 3/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
SGMS2 Q8NHU3 3/20 0.40
FABP3 P05413 1/20 0.39
HTR1A P08908 1/20 0.39
HTR7 P34969 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375528 0.88 LPAR1 (0.42) LPAR1FABP4FABP5PTGDR2SGMS2
SCHEMBL15402113 0.88 L3MBTL1 (0.40) LPAR1LMNAHTTHDAC8GAA
SCHEMBL15401949 0.87 PTGDR2 (0.44) LPAR1FABP4FABP5PTGDR2FABP3
SCHEMBL15401682 0.87 PTGDR2 (0.46) FABP4FABP5PTGDR2SGMS2FABP3
SCHEMBL15402503 0.87 PTGDR2 (0.49) FABP4FABP5PTGDR2SGMS2FABP3
SCHEMBL15401975 0.87 LMNA (0.43) LPAR1FABP4FABP5LMNAKMT2A
SCHEMBL15375472 0.81 FABP4 (0.43) LPAR1FABP4FABP5PTGDR2SGMS2
SCHEMBL15402604 0.81 BCHE (0.38) LPAR1FABP4FABP5KMT2AMEN1
SCHEMBL15401896 0.80 PTGDR2 (0.46) PTGDR2SGMS2LMNAHTTHDAC8
SCHEMBL15375550 0.79 SGMS2 (0.41) LPAR1FABP4FABP5PTGDR2SGMS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA LPAR1 3283/4885FABP4 4349/4885FABP5 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.