Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL2459027 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28335077 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL10494124 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL3714697 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL2459025 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1680010 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL317388 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28885521 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL29050229 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL29050228 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150201615-A1 | INSECT REPELLENT SURFACE COMPOSITION | ENVANCE TECHNOLOGIES, LLC | 2015-07-23 | — | — | US | claimed |
| EP-2866568-A1 | INSECT REPELLENT SURFACE COMPOSITION | Tyratech, Inc. (US) | 2015-05-06 | — | — | EP | claimed |
| WO-2014005034-A1 | INSECT REPELLENT SURFACE COMPOSITION | TYRATECH, INC. (US) | 2014-01-03 | — | — | WO | claimed |
| EP-4692291-A1 | FOAM INHIBITOR COMPOSITION, CONCENTRATED TRANSPARENT LIQUID DETERGENT FOR HOUSEHOLD WASHING, AND PRODUCTION METHOD FOR SAME | Dow Toray Co., Ltd. (JP) | 2026-02-11 | — | — | EP | disclosed |
| CN-116670326-A | Copper component | 纳美仕有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116034632-A | Wiring for multilayer substrate and method for manufacturing the same | 纳美仕有限公司 | 2023-04-28 | — | — | CN | disclosed |
| US-20190208778-A1 | INSECT REPELLENT SURFACE COMPOSITION | ENVANCE TECH LLC (US) | 2019-07-11 | — | — | US | disclosed |
| US-20190208778-A1 | INSECT REPELLENT SURFACE COMPOSITION | ENVANCE TECH LLC (US) | 2019-07-11 | — | — | US | disclosed |
| US-20150201615-A1 | INSECT REPELLENT SURFACE COMPOSITION | ENVANCE TECHNOLOGIES, LLC | 2015-07-23 | — | — | US | disclosed |
| US-20150201615-A1 | INSECT REPELLENT SURFACE COMPOSITION | ENVANCE TECHNOLOGIES, LLC | 2015-07-23 | — | — | US | disclosed |
| EP-2866568-A1 | INSECT REPELLENT SURFACE COMPOSITION | Tyratech, Inc. (US) | 2015-05-06 | — | — | EP | disclosed |
| EP-2866568-A1 | INSECT REPELLENT SURFACE COMPOSITION | Tyratech, Inc. (US) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014005034-A1 | INSECT REPELLENT SURFACE COMPOSITION | TYRATECH, INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| WO-2014005034-A1 | INSECT REPELLENT SURFACE COMPOSITION | TYRATECH, INC. (US) | 2014-01-03 | — | — | WO | disclosed |