Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL2459027 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL15401937 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28335077 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL10494124 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL3714697 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1680010 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL317388 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28885521 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL29050229 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL29050228 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4422422-A1 | COMPOSITION FOR ENHANCING SPICY FLAVOR AND FOOD | AJINOMOTO CO., INC. (JP) | 2024-09-04 | — | — | EP | claimed |
| US-20240075457-A1 | METHOD OF FORMING INTEGRATED COMPOSITE COMPRISING CONDUCTIVE CARBON NETWORK | SUSTAERA INC (US) | 2024-03-07 | — | — | US | claimed |
| CN-113088486-B | Non-enzymatic hydrolysate for separating adherent cells and preparation method thereof | 广东为象生物科技有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-116218575-A | Chelated iron desulfurizing agent | 中海石油(中国) 有限公司深圳分公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2023074853-A1 | COMPOSITION FOR ENHANCING SPICY FLAVOR AND FOOD | AJINOMOTO CO., INC. (JP) | 2023-05-04 | — | — | WO | claimed |
| WO-2023035284-A1 | L-ASPARTIC ACID N, N-DIACETIC ACID TETRASODIUM SALT AND PREPARATION METHOD THEREFOR | 合肥艾普拉斯环保科技有限公司 | 2023-03-16 | — | — | WO | claimed |
| US-20230061502-A1 | PROTECTIVE COMPOSITIONS FOR USE IN SYSTEMS COMPRISING INDUSTRIAL WATER | SOLUGEN, INC. (US) | 2023-03-02 | — | — | US | claimed |
| CN-115684584-A | EB virus magnetic particle chemiluminescence detection kit | 郑州安图生物工程股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| US-20220411295-A1 | MULTIFUNCTIONAL ADDITIVE | SOLUGEN, INC. (US) | 2022-12-29 | — | — | US | claimed |
| EP-4100142-A1 | PROTECTIVE COMPOSITIONS FOR USE IN SYSTEMS COMPRISING INDUSTRIAL WATER | Solugen, Inc. (US) | 2022-12-14 | — | — | EP | claimed |
| CN-101543744-B | Multi-component composite water-coal-slurry dispersant and application thereof | BEIJING HONGYANG ZIDONG ENVIRONMENTAL PROT SCI TECH CO LTD | 2011-08-31 | — | — | CN | claimed |
| CN-101717509-B | Method for synthesizing polyaspartic acid by utilizing ionic liquid | UNIV HEILONGJIANG | 2011-07-20 | — | — | CN | claimed |
| CN-101717509-A | Method for synthesizing polyaspartic acid by utilizing ionic liquid | UNIV HEILONGJIANG | 2010-06-02 | — | — | CN | claimed |
| CN-101543744-A | Multi-component composite water-coal-slurry dispersant and application thereof | BEIJING ZIDONG ENVIRONMENTAL P | 2009-09-30 | — | — | CN | claimed |
| US-7122201-B2 | Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma using surfactants and amino acids | BAXTER INTERNATIONAL INC. (US) | 2006-10-17 | — | — | US | claimed |
| US-20030032639-A1 | Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma using surfactants and amino acids | WYETH (US) | 2003-02-13 | — | — | US | claimed |
| WO-2003002150-A1 | COMPOSITION AND METHOD FOR REDUCING ADVERSE INTERACTIONS BETWEEN PHENOTHIAZINE DERIVATIVES AND PLASMA | WYETH (US) | 2003-01-09 | — | — | WO | claimed |
| CN-1045308-C | Novel water-soluble metalworking fluids | SUOLUTIA CO (US) | 1999-09-29 | — | — | CN | claimed |
| CN-1135234-A | Novel water-soluble metalworking fluids | MONSANTO CO (US) | 1996-11-06 | — | — | CN | claimed |
| CN-1079900-A | 1,6-fructose diphosphate sodium oral liquid | OYANG PINGKAI (CN) | 1993-12-29 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032639-A1 | Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma using surfactants and amino acids | PHOSPHO1, AADAT, SLC7A5 | GRIK1 398/4885GRIK2 359/4885GRM1 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.