Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15409673 | 1.00 | KCNH2 (0.44) | KCNH2PTGS2HTR2ACYP19A1HSD11B1 | |
| SCHEMBL12817653 | 0.93 | HSD11B1 (0.41) | KCNH2PTGS2HSD11B1CYP3A4TDP1 | |
| SCHEMBL12817664 | 0.93 | HSD11B1 (0.41) | KCNH2PTGS2HSD11B1CYP3A4TDP1 | |
| SCHEMBL12817106 | 0.82 | PTGS2 (0.44) | PTGS2HTR2ACYP3A4GPR84 | |
| SCHEMBL15410774 | 0.82 | PTGS2 (0.44) | PTGS2HTR2ACYP3A4GPR84 | |
| Hexane SCHEMBL1984798 | 0.80 | HTT (0.39) | KCNH2CYP19A1GPR84 | |
| SCHEMBL10320192 | 0.80 | HSD11B1 (0.50) | KCNH2PTGS2HTR2AHSD11B1CYP3A4 | |
| SCHEMBL10319574 | 0.80 | HSD11B1 (0.50) | KCNH2PTGS2HTR2AHSD11B1CYP3A4 | |
| SCHEMBL12816526 | 0.79 | TP53 (0.44) | PTGS2CYP19A1L3MBTL1 | |
| SCHEMBL12815746 | 0.79 | TP53 (0.44) | PTGS2CYP19A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937195-B2 | Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20140018564-A1 | METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-16 | — | — | US | disclosed |