Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16912725 | 0.82 | MEN1 (0.51) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL15413553 | 0.81 | ELANE (0.47) | MEN1KMT2AELANEALDH1A1CYP3A4 | |
| SCHEMBL15413504 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL15413406 | 0.76 | PSMB11 (0.62) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL12519192 | 0.71 | MEN1 (0.69) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL19638063 | 0.70 | CA1 (0.41) | KMT2AMAPTTSHRMAPK1KDM4E | |
| SCHEMBL29928697 | 0.69 | ALDH1A1 (0.74) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL8199540 | 0.69 | ALDH1A1 (0.74) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL23486119 | 0.69 | MEN1 (0.75) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL22909075 | 0.69 | ALDH1A1 (0.62) | MEN1KMT2AMAOAMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872474-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | Georgia State University Research Foundation, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011753-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-01-16 | — | — | WO | disclosed |