Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | ELANE | P08246 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656217 | 0.84 | TTR (0.60) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL15413406 | 0.84 | PSMB11 (0.62) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL29928697 | 0.82 | ALDH1A1 (0.74) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL8199540 | 0.82 | ALDH1A1 (0.74) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL22909075 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL16912725 | 0.81 | MEN1 (0.51) | ALDH1A1MAPTTSHRTDP1MAOA | |
| Danthron SCHEMBL29356886 | 0.79 | MAPT (1.00) | ALDH1A1MAPTTSHRTDP1MAOA | |
| Danthron SCHEMBL30544826 | 0.79 | MAPT (1.00) | ALDH1A1MAPTTSHRTDP1MAOA | |
| Danthron SCHEMBL83688 | 0.79 | MAPT (1.00) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL15413385 | 0.79 | MEN1 (0.49) | ALDH1A1MAPTTSHRTDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| CN-110526827-A | Anthraquinone analogs and its preparation and application | UNIV GEORGIA STATE RES FOUND | 2019-12-03 | — | — | CN | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| EP-2872474-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | Georgia State University Research Foundation, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| CN-104507902-A | Anthraquinone analogs and methods of making and using the same | UNIV GEORGIA STATE RES FOUND | 2015-04-08 | — | — | CN | disclosed |
| WO-2014011753-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | PCNA, KRAS, RECQL | ALDH1A1 1562/4885MAPT 4878/4885TSHR 4555/4885 |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | ALDH1A1 1562/4885MAPT 4878/4885TSHR 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.