Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427184 | 0.85 | TTR (0.56) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL15427133 | 0.83 | TTR (0.46) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL15427164 | 0.82 | TTR (0.45) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL15427128 | 0.82 | ELANE (0.50) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL28364252 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL15427185 | 0.81 | TTR (0.42) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL8996312 | 0.81 | TTR (0.71) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL15427084 | 0.81 | TTR (0.43) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL15427167 | 0.80 | TTR (0.42) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL16919800 | 0.80 | TTR (0.44) | MEN1KMT2ATTRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872474-B1 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2022-01-19 | — | — | EP | disclosed |
| EP-2872474-B1 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2022-01-19 | — | — | EP | disclosed |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| EP-2872474-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | Georgia State University Research Foundation, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011753-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-2014011753-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | PCNA, KRAS, RECQL | MEN1 677/4885KMT2A 1122/4885TTR 4284/4885 |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | MEN1 677/4885KMT2A 1122/4885TTR 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.