SCHEMBL28364252

SCHEMBL28364252

COc1cccc2c1C(=O)c1c(OC)cc(OC(=O)N=[N+]=[N-])cc1C2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
EGFR P00533 1/20 0.46
PIM1 P11309 1/20 0.46
ELANE P08246 12/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.42
ABCC4 O15439 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
TTR P02766 1/20 0.42
TP53 P04637 1/20 0.42
HSP90AA1 P07900 1/20 0.42
CHRM2 P08172 1/20 0.42
HSP90AB1 P08238 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15413441 0.81 MEN1 (0.49) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL8947495 0.72 EGFR (0.73) ALDH1A1EGFRPIM1ELANEMEN1
SCHEMBL16921218 0.72 EGFR (0.43) ALDH1A1EGFRPIM1ELANEMEN1
SCHEMBL16226324 0.71 ALDH1A1 (0.69) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL16225768 0.71 EGFR (0.64) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL8996312 0.71 TTR (0.71) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL9878296 0.70 ELANE (0.60) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL8996338 0.70 MEN1 (0.55) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL8996346 0.69 EGFR (0.56) ALDH1A1CYP1A2CYP3A4EGFRPIM1
SCHEMBL15413483 0.69 EGFR (0.56) ALDH1A1CYP1A2CYP3A4EGFRPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110526827-A Anthraquinone analogs and its preparation and application UNIV GEORGIA STATE RES FOUND 2019-12-03 CN disclosed