SCHEMBL155668

SCHEMBL155668

O=C(c1ccccc1)c1ccccc1-n1cc(O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)c2c(Cl)c(Br)ccc21

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 3/20 0.40
SLC5A1 P13866 1/20 0.40
TYMP P19971 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC28A3 Q9HAS3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27856153 1.00 SLC5A2 (0.40) SLC5A2SLC5A1TYMPATMHSD17B10
SCHEMBL155667 1.00 SLC5A2 (0.40) SLC5A2SLC5A1TYMPATMHSD17B10
SCHEMBL155666 0.90 HK1 (0.33) SLC5A2SLC5A1
SCHEMBL155034 0.90 SLC28A3 (0.45) SLC5A2SLC5A1ATMSLC28A3
SCHEMBL155035 0.90 SLC28A3 (0.45) SLC5A2SLC5A1ATMSLC28A3
SCHEMBL154137 0.88 APP (0.41) SLC5A2SLC5A1ATMSLC28A3
SCHEMBL154136 0.88 APP (0.41) SLC5A2SLC5A1ATMSLC28A3
SCHEMBL28795196 0.88 APP (0.41) SLC5A2SLC5A1ATMSLC28A3
SCHEMBL156536 0.87 SLC5A2 (0.46) SLC5A2SLC5A1SLC28A3
SCHEMBL156535 0.87 SLC5A2 (0.46) SLC5A2SLC5A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940909-B2 Indicator platform BIOSYNTH AG (CH) 2015-01-27 US disclosed
EP-2427431-B1 NOVEL INDICATOR PLATFORM BIOSYNTH AG (CH) 2013-05-01 EP disclosed
EP-2427431-A1 NOVEL INDICATOR PLATFORM Biosynth AG (CH) 2012-03-14 EP disclosed
US-20120058503-A1 Novel Indicator Platform BIOSYNTH AG (CH) 2012-03-08 US disclosed
EP-2256103-A1 Novel indicator platform Biosynth AG (CH) 2010-12-01 EP disclosed
WO-2010128120-A1 NOVEL INDICATOR PLATFORM BIOSYNTH AG (CH) 2010-11-11 WO disclosed