Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159726 | 0.81 | KIF11 (0.49) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10434357 | 0.80 | KIF11 (0.47) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9502784 | 0.80 | KIF11 (0.47) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5673595 | 0.80 | KIF11 (0.61) | KIF11GABRPGABRDGABRA1GABRB1 | |
| Benzene SCHEMBL26657973 | 0.80 | KIF11 (0.47) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8742022 | 0.78 | MAPT (0.49) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28172630 | 0.78 | TDO2 (0.45) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL67665 | 0.77 | KIF11 (0.55) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27667691 | 0.77 | KIF11 (0.47) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11667136 | 0.76 | MAPT (0.44) | KIF11GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11674135-B2 | DNA-encoded libraries having encoding oligonucleotide linkages not readable by polymerases | X-CHEM, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| EP-3851529-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3392338-B1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X CHEM INC (US) | 2020-12-09 | — | — | EP | disclosed |
| US-20200143903-A1 | METHODS FOR IDENTIFYING COMPOUNDS | MIDCAP FINANCIAL TRUST | 2020-05-07 | — | — | US | disclosed |
| EP-3612545-A1 | METHODS FOR IDENTIFYING COMPOUNDS | X-Chem, Inc. (US) | 2020-02-26 | — | — | EP | disclosed |
| WO-2018195134-A1 | METHODS FOR IDENTIFYING COMPOUNDS | X-CHEM, INC. (US) | 2018-10-25 | — | — | WO | disclosed |
| EP-3392338-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-2872680-B1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X CHEM INC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-20180002688-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2018-01-04 | — | — | US | disclosed |
| EP-3240795-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-Chem, Inc. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109423-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| US-20150211002-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | PHARMACEUTICAL PRODUCT DEVELOPMENT, LLC | 2015-07-30 | — | — | US | disclosed |
| EP-2872680-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014012010-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-CHEM, INC. (US) | 2014-01-16 | — | — | WO | disclosed |