Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | RET | P07949 | 7/20 | 0.33 |
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282700 | 0.85 | CYP3A4 (0.37) | CYP3A4GPR119RETPPIA | |
| SCHEMBL21639716 | 0.85 | CYP3A4 (0.37) | CYP3A4GPR119RETPPIA | |
| SCHEMBL16909354 | 0.83 | CYP3A4 (0.36) | CYP3A4GPR119RETPPIA | |
| SCHEMBL392092 | 0.76 | USP2 (0.44) | GPR119USP2TSHR | |
| SCHEMBL28713485 | 0.76 | RET (0.41) | RET | |
| SCHEMBL20069299 | 0.75 | NPC1 (0.39) | CYP3A4GPR119PPIAUSP2MEN1 | |
| SCHEMBL1820679 | 0.75 | MAPT (0.39) | PPIAMEN1KMT2A | |
| SCHEMBL1282440 | 0.74 | PANK3 (0.39) | CYP3A4GPR119RET | |
| SCHEMBL3215428 | 0.74 | DRD2 (0.41) | PPIAUSP2MEN1KMT2AHSD17B10 | |
| SCHEMBL28719905 | 0.74 | RET (0.42) | RETKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872508-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SPRL (BE) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009295-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB PHARMA S.A. (BE) | 2014-01-16 | — | — | WO | disclosed |