Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.52 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.52 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593419 | 0.91 | RAB9A (1.00) | RAB9ASMN1; SMN2TP53HDAC6LMNA | |
| SCHEMBL31329340 | 0.91 | RAB9A (1.00) | RAB9ASMN1; SMN2TP53HDAC6LMNA | |
| SCHEMBL27915817 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53LMNAMEN1 | |
| SCHEMBL27915820 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53LMNAMEN1 | |
| SCHEMBL3236154 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53HDAC6LMNA | |
| SCHEMBL31329346 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53HDAC6LMNA | |
| SCHEMBL31329353 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53HDAC6LMNA | |
| SCHEMBL27915818 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53HDAC6LMNA | |
| SCHEMBL31329347 | 0.85 | RAB9A (0.77) | RAB9ASMN1; SMN2TP53LMNAMEN1 | |
| SCHEMBL17487385 | 0.84 | RAB9A (0.58) | RAB9ASMN1; SMN2TP53HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633175-B2 | Compounds as antagonists or inverse agonists at opioid receptors | GLAXOSMITHKLINE LLC (US) | 2014-01-21 | — | — | US | disclosed |