Sugi Predict

Sugi Predict / Compounds / SCHEMBL3593419

SCHEMBL3593419

SCHEMBL3593419

c1ccc(CNc2nc3ccccc3[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 4/20 1.00
▸ SMN1; SMN2 Q16637 3/20 1.00
▸ TP53 P04637 2/20 1.00
▸ LMNA P02545 2/20 0.68
▸ GFER P55789 2/20 0.68
▸ HTT P42858 1/20 0.68
▸ HIF1A Q16665 1/20 0.68
▸ GAA P10253 4/20 0.60
▸ MEN1 O00255 3/20 0.60
▸ KMT2A Q03164 3/20 0.60
▸ NPC1 O15118 1/20 0.60
▸ ALDH1A1 P00352 2/20 0.59
▸ MAPK1 P28482 2/20 0.59
▸ MAPT P10636 2/20 0.59
▸ POLB P06746 2/20 0.59
▸ KDM4E B2RXH2 1/20 0.59
▸ HDAC6 Q9UBN7 1/20 0.59
▸ BCHE P06276 1/20 0.58
▸ TRPC3 Q13507 1/20 0.58
▸ TRPC4 Q9UBN4 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31329340 1.00 RAB9A (1.00) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL15416993 0.91 RAB9A (0.82) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL27915818 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL27915817 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL3236154 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL31329347 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL27915820 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL31329346 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL31329353 0.87 RAB9A (0.77) RAB9ASMN1; SMN2TP53LMNAGFER
SCHEMBL8209736 0.86 RAB9A (0.75) RAB9ASMN1; SMN2TP53LMNAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119318653-A Application of benzimidazole amine derivatives in medicines for preventing/treating non-alcoholic fatty liver disease 常州大学 2025-01-17 — — CN disclosed
US-20210219546-A1 METHODS OF TREATING CROP PLANTS ALTER DOMUS US LLC 2021-07-22 — — US disclosed
EP-3294052-A1 METHODS OF TREATING CROP PLANTS Agrofresh, Inc. (US) 2018-03-21 — — EP disclosed
CN-107592788-A The method for handling crop plants 阿格洛法士公司 2018-01-16 — — CN disclosed
US-20170362184-A1 PRO-SURVIVAL COMPOUNDS HERIOT-WATT UNIVERSITY (GB) 2017-12-21 — — US disclosed
WO-2016182995-A1 METHODS OF TREATING CROP PLANTS AGROFRESH INC (US) 2016-11-17 — — WO disclosed
US-20150282479-A1 METHODS OF TREATING CROP PLANTS AGROFRESH, INC. 2015-10-08 — — US disclosed
US-9055741-B2 Contacting crop plants with compositions ROHM AND HAAS COMPANY (US) 2015-06-16 — — US disclosed
EP-1856976-B1 Contacting crop plants with compositions ROHM & HAAS (US) 2014-09-03 — — EP disclosed
CN-103044337-A Synthetic method of 2-(N-alkyl)aminooimidazole derivatives UNIV NANJING SCIENCE & TECH 2013-04-17 — — CN disclosed
US-5874501-A POLY(P-HYDROXYSTYRENE) WITH AROMATIC MOIETY AND ALIPHATIC MOIETY WITH INORGANIC OXIDE KEEHAN DONALD J (US) 1999-02-23 — — US disclosed
EP-0407554-B1 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS KEEHAN DONALD J (US) 1997-09-17 — — EP disclosed
US-5658996-A A LIQUID POLYEPOXIDE PREPOLYMER THE REACTION PRODUCT OF A TRISHYDROXYPHENYL, AN AROMATIC DIGLYCIDYL ETHER AND METAL OXIDE; CURABLE, LOW VISCOSITY; FORMED POLYEPOXIDE IS HEAT AND CHEMICAL RESISTANCE, ELONGATION, TOUGHNESS KEEHAN DONALD J (US) 1997-08-19 — — US disclosed
US-5169912-A Hydrolyzable oxygen bonding with epoxide; silica, titania; high performance coatings, adhesives KEEHAN DONALD J (US) 1992-12-08 — — US disclosed
US-5026816-A Reaction product of diglycidyl ether of (bisphenol a or resorcinol) with metallic oxide in presence of imidazole catalyst KEEHAN DONALD J (US) 1991-06-25 — — US disclosed
US-4880892-A PHOSPHONIUM OR PHOSPHORANE CATALYST, PROTECTIVE COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 — — US disclosed
EP-0233040-A2 Stigma of crocus sativus L. and method for the production thereof AJINOMOTO CO., INC. (JP) 1987-08-19 — — EP disclosed
EP-0005318-B1 N-HETEROCYCLYL-4-PIPERIDINAMINES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, INTERMEDIATES THEREFOR, AND METHOD FOR THE PREPARATION OF THE INTERMEDIATES JANSSEN PHARMACEUTICA N.V. (BE) 1982-01-06 — — EP disclosed
US-4219559-A N-Heterocyclyl-4-piperidinamines JANSSEN PHARMACEUTICA N.V. (BE) 1980-08-26 — — US disclosed
EP-0005318-A1 N-Heterocyclyl-4-piperidinamines, methods for their preparation, pharmaceutical compositions comprising them, intermediates therefor, and method for the preparation of the intermediates JANSSEN PHARMACEUTICA N.V. (BE) 1979-11-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150282479-A1 METHODS OF TREATING CROP PLANTS CYCS, NOP2, CNPY3 RAB9A 3842/4885SMN1; SMN2 4017/4885TP53 3868/4885
US-20170362184-A1 PRO-SURVIVAL COMPOUNDS MCL1, MKI67, MORF4L1 RAB9A 2097/4885SMN1; SMN2 10/4885TP53 32/4885
US-20210219546-A1 METHODS OF TREATING CROP PLANTS CYCS, NOP2, CNPY3 RAB9A 3842/4885SMN1; SMN2 4017/4885TP53 3868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.