Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16395116 | 0.95 | ESR1 (0.44) | TAS1R3TAS1R1ESR1L3MBTL1GAA | |
| SCHEMBL3422632 | 0.91 | CYP19A1 (0.41) | TAS1R3TAS1R1CYP19A1ESR1L3MBTL1 | |
| SCHEMBL16405355 | 0.89 | KDM4E (0.41) | ESR1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL11925426 | 0.87 | VDR (0.42) | TAS1R3TAS1R1ESR1L3MBTL1GAA | |
| SCHEMBL13865066 | 0.86 | L3MBTL1 (0.46) | TAS1R3TAS1R1L3MBTL1GAAKDM4E | |
| SCHEMBL2608608 | 0.86 | TSHR (0.47) | CYP19A1ESR1GAAHTTKDM4E | |
| SCHEMBL12445352 | 0.85 | L3MBTL1 (0.42) | TAS1R3TAS1R1CYP19A1L3MBTL1HTT | |
| SCHEMBL12358776 | 0.85 | CNR1 (0.41) | ESR1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL16841430 | 0.85 | GAA (0.39) | TAS1R3TAS1R1CYP19A1ESR1GAA | |
| SCHEMBL10015729 | 0.84 | TSHR (0.46) | CYP19A1ESR1GAAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623578-B2 | Tetraaryl polycarbonate containing photoconductors | XEROX CORPORATION (US) | 2014-01-07 | — | — | US | disclosed |