Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.71 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12215285 | 0.90 | CNR1 (0.85) | CNR1CNR2EPHX2STSALDH1A1 | |
| SCHEMBL16762031 | 0.89 | CNR1 (0.82) | CNR1CNR2EPHX2STSALDH1A1 | |
| SCHEMBL933945 | 0.84 | CNR1 (0.76) | CNR1CNR2EPHX2STSTRPV1 | |
| SCHEMBL15417417 | 0.83 | HPGD (0.71) | CNR1CNR2EPHX2STSTRPV1 | |
| SCHEMBL15417418 | 0.83 | EPHX2 (0.83) | EPHX2TRPV1ALDH1A1 | |
| SCHEMBL18255425 | 0.83 | CNR1 (1.00) | CNR1CNR2EPHX2TRPV1 | |
| SCHEMBL2795232 | 0.83 | NPC1 (0.61) | CNR1CNR2ALDH1A1 | |
| SCHEMBL12127405 | 0.81 | CNR1 (0.67) | CNR1CNR2ALDH1A1 | |
| SCHEMBL20399568 | 0.81 | CNR1 (0.70) | CNR1CNR2EPHX2STSTRPV1 | |
| SCHEMBL9234996 | 0.80 | CNR1 (0.54) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8624063-B2 | Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-01-07 | — | — | US | disclosed |