Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933858 | 0.88 | NPC1 (0.67) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL12470513 | 0.86 | NPC1 (0.60) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL5250976 | 0.83 | NPC1 (0.69) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL5902331 | 0.83 | NPC1 (0.65) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL2797868 | 0.83 | NPC1 (0.65) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL15417367 | 0.83 | CNR1 (0.71) | ALDH1A1CNR1CNR2 | |
| SCHEMBL12127405 | 0.82 | CNR1 (0.67) | NPC1GAAALDH1A1PKMCNR1 | |
| SCHEMBL7529534 | 0.80 | NPC1 (0.65) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL16215809 | 0.80 | NPC1 (0.65) | NPC1GAAALDH1A1PKMRAB9A | |
| SCHEMBL8288439 | 0.80 | NPC1 (0.65) | NPC1GAAALDH1A1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168175-A1 | ATPENINS | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| WO-2010069495-A1 | ATPENINS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168175-A1 | ATPENINS | ATP5ME, ATP5MK, ATP5F1B | NPC1 3373/4885GAA 1667/4885ALDH1A1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.