Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106807 | 0.98 | FFAR4 (0.36) | FFAR4ACACBACACAFFAR1CYP4F2 | |
| SCHEMBL1106809 | 0.93 | FFAR4 (0.39) | FFAR4ACACBACACAFFAR1CYP4F2 | |
| SCHEMBL1106810 | 0.91 | FFAR4 (0.36) | FFAR4ACACBACACAFFAR1CYP4F2 | |
| SCHEMBL798303 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11 | |
| SCHEMBL10091370 | 0.85 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL13818712 | 0.85 | ACACB (0.67) | FFAR4ACACBACACAFFAR1CYP4F2 | |
| SCHEMBL1106814 | 0.83 | TRPA1 (0.35) | FFAR4ACACBACACAFFAR1ALDH1A1 | |
| SCHEMBL186576 | 0.82 | FFAR4 (0.40) | FFAR4ACACBACACAFFAR1CYP4F2 | |
| SCHEMBL18633532 | 0.81 | FFAR4 (0.39) | FFAR4ACACBACACAFFAR1CYP4F2 | |
| SCHEMBL1106784 | 0.81 | LMNA (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623915-B2 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. (US) | 2014-01-07 | — | — | US | disclosed |