SCHEMBL15417591

SCHEMBL15417591

CCOc1cccc(P(c2ccccc2)c2ccccc2)c1-c1c(OCC)cccc1P(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 6/20 0.42
GLA P06280 1/20 0.42
PDK2 Q15119 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
DRD1 P21728 2/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTR1A P08908 2/20 0.36
ADRA1D P25100 2/20 0.36
ADRA1A P35348 2/20 0.36
ADRA1B P35368 2/20 0.36
TTR P02766 1/20 0.36
PTPRC P08575 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023141 1.00 ALDH1A1 (0.43) ALDH1A1L3MBTL1GLAPDK2MAPT
SCHEMBL9181053 0.87 ALDH1A1 (0.47) ALDH1A1L3MBTL1GLAMAPTNPSR1
SCHEMBL30707397 0.87 ALDH1A1 (0.47) ALDH1A1L3MBTL1GLAMAPTNPSR1
SCHEMBL14467009 0.87 MCHR1 (0.38) L3MBTL1MAPTDRD1TDP1CYP3A4
SCHEMBL30171081 0.85 ALDH1A1 (0.42) ALDH1A1L3MBTL1GLAMAPTNPSR1
SCHEMBL1833246 0.84 ALDH1A1 (0.47) ALDH1A1L3MBTL1GLAMAPTNPSR1
SCHEMBL1752346 0.81 MAPT (0.51) L3MBTL1MAPTTDP1HTR1AADRA1D
SCHEMBL301296 0.80 CA1 (0.44) ALDH1A1L3MBTL1MAPTDRD1TDP1
SCHEMBL29407955 0.80 CA1 (0.44) ALDH1A1L3MBTL1MAPTDRD1TDP1
SCHEMBL29430119 0.80 CA1 (0.44) ALDH1A1L3MBTL1MAPTDRD1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623621-B2 Method for producing optically active 2-methyl-alkanols BASF SE (DE) 2014-01-07 US disclosed