Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118801 | 0.89 | CA1 (0.38) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL13210497 | 0.82 | LMNA (0.58) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL2971851 | 0.82 | LMNA (0.58) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL1151641 | 0.82 | LMNA (0.58) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL8508528 | 0.82 | LMNA (0.58) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL16586895 | 0.82 | LMNA (0.48) | LMNAF2TSHRTDP1TP53 | |
| Benzene SCHEMBL27793442 | 0.81 | LMNA (0.70) | LMNAF2TSHRTDP1TP53 | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.81 | LMNA (0.70) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL52413 | 0.81 | LMNA (0.70) | LMNAF2TSHRTDP1TP53 | |
| Benzoyl Chloride SCHEMBL28645107 | 0.80 | LMNA (0.56) | LMNAF2TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102558064-B | Antihypertensive compound, and its preparation method, application and pharmaceutically acceptable salts and solvates | ARROMAX PHARMATECH CO LTD | 2014-04-16 | — | — | CN | disclosed |
| US-20140041541-A1 | POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND A METHOD FOR MAKING A PRINTING PLATE | KODAK (NEAR EAST) INC. | 2014-02-13 | — | — | US | disclosed |
| EP-2687905-A1 | POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING SAME | Eastman Kodak Company (US) | 2014-01-22 | — | — | EP | disclosed |
| CN-102558064-A | Antihypertensive compound, and its preparation method, application and pharmaceutically acceptable salts and solvates | ARROMAX PHARMATECH CO LTD | 2012-07-11 | — | — | CN | disclosed |
| CN-101018829-A | Cyanopyridine-based azo dyes | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2007-08-15 | — | — | CN | disclosed |
| CN-1269640-C | Litho-printing panel for infrared laser | FUJI PHOTO FILM CO LTD (JP) | 2006-08-16 | — | — | CN | disclosed |
| CN-1235089-C | Photosensitive lithographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2006-01-04 | — | — | CN | disclosed |
| CN-1406748-A | Litho-printing panel for infrared laser | FUJI PHOTO FILM CO LTD (JP) | 2003-04-02 | — | — | CN | disclosed |
| CN-1355448-A | Photosensitive lithographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2002-06-26 | — | — | CN | disclosed |