Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 8/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11897519 | 0.97 | TSHR (0.40) | FAAHNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL15418090 | 0.93 | PRKDC (0.39) | FAAHNPC1RAB9ASMN1; SMN2BRS3 | |
| SCHEMBL15418062 | 0.90 | TSHR (0.36) | FAAHSMN1; SMN2BRS3AGTR1AGTR2 | |
| SCHEMBL15418015 | 0.88 | BRS3 (0.40) | FAAHBRS3MMEFFAR1AKR1B1 | |
| SCHEMBL1370921 | 0.87 | TSHR (0.39) | FAAHSMN1; SMN2BRS3TSHRALDH1A1 | |
| SCHEMBL9710320 | 0.84 | MME (0.51) | BRS3AGTR1AGTR2TSHRMME | |
| SCHEMBL9710577 | 0.83 | MME (0.50) | BRS3AGTR1AGTR2TSHRMME | |
| SCHEMBL9710219 | 0.83 | MME (0.50) | BRS3AGTR1AGTR2TSHRMME | |
| SCHEMBL1374077 | 0.83 | MAPT (0.39) | SMN1; SMN2BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL16457755 | 0.83 | PRKDC (0.37) | FAAHBRS3TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687523-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | Kowa Company Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |