Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | BRS3 | P32247 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370921 | 0.97 | TSHR (0.39) | TSHRFAAHSMN1; SMN2MMEALDH1A1 | |
| SCHEMBL16457755 | 0.93 | PRKDC (0.37) | TSHRFAAHMMEALDH1A1S1PR1 | |
| SCHEMBL15418005 | 0.90 | FAAH (0.40) | TSHRFAAHSMN1; SMN2MMEALDH1A1 | |
| SCHEMBL16458596 | 0.89 | PPARG (0.36) | TSHRSMN1; SMN2MAPTMMEALDH1A1 | |
| SCHEMBL11897519 | 0.87 | TSHR (0.40) | TSHRFAAHSMN1; SMN2MMES1PR1 | |
| SCHEMBL1374077 | 0.85 | MAPT (0.39) | SMN1; SMN2MAPTALDH1A1BRS3L3MBTL1 | |
| SCHEMBL1371403 | 0.85 | MME (0.48) | TSHRMMEALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL15418090 | 0.83 | PRKDC (0.39) | TSHRFAAHSMN1; SMN2MMES1PR1 | |
| SCHEMBL633444 | 0.82 | MME (0.48) | TSHRMMEPPARGFFAR1AKR1B1 | |
| SCHEMBL27948271 | 0.81 | ANPEP (0.36) | TSHRSMN1; SMN2MAPTBRS3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315493-B2 | Phenylpyridine derivative and drug containing same | KOWA COMPANY, LTD. (JP) | 2016-04-19 | — | — | US | disclosed |
| EP-2687523-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA CO (JP) | 2016-01-06 | — | — | EP | disclosed |
| CN-103459380-B | Phenylpyridine derivative and medicine containing the same | KOWA CO | 2015-07-15 | — | — | CN | disclosed |
| EP-2687523-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | Kowa Company Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140011823-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA COMPANY, LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| CN-103459380-A | Novel phenylpyridine derivative and medicine containing the same | KOWA CO | 2013-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011823-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | AGTR2, AGTR1, PPARD | TSHR 289/4885FAAH 2489/4885SMN1; SMN2 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.