Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11897519 | 0.94 | TSHR (0.40) | PRKDCATMATRBRS3MME | |
| SCHEMBL15418005 | 0.93 | FAAH (0.40) | PRKDCATMATRBRS3MME | |
| SCHEMBL15418015 | 0.91 | BRS3 (0.40) | PRKDCATMATRBRS3MME | |
| SCHEMBL1374077 | 0.90 | MAPT (0.39) | PRKDCATMATRBRS3FFAR1 | |
| SCHEMBL16457755 | 0.90 | PRKDC (0.37) | PRKDCATMATRBRS3MME | |
| SCHEMBL1370921 | 0.84 | TSHR (0.39) | PRKDCATMATRBRS3MME | |
| SCHEMBL15418062 | 0.83 | TSHR (0.36) | PRKDCATMATRBRS3MME | |
| SCHEMBL8317308 | 0.83 | MME (0.54) | BRS3MMEFFAR1AKR1B1PTPN1 | |
| SCHEMBL16458596 | 0.81 | PPARG (0.36) | PRKDCATMATRBRS3MME | |
| SCHEMBL8316083 | 0.78 | MME (0.53) | BRS3MMEFFAR1AKR1B1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687523-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | Kowa Company Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |