⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16457601 | 1.00 | — | — | |
| SCHEMBL9948302 | 0.96 | AGTR1 (0.32) | — | |
| SCHEMBL9948301 | 0.96 | AGTR1 (0.32) | — | |
| SCHEMBL16457930 | 0.95 | MAPT (0.33) | — | |
| SCHEMBL15419384 | 0.95 | MAPT (0.33) | — | |
| SCHEMBL16458199 | 0.94 | — | — | |
| SCHEMBL15418034 | 0.94 | — | — | |
| SCHEMBL9947998 | 0.90 | APLNR (0.35) | — | |
| SCHEMBL9947999 | 0.90 | APLNR (0.35) | — | |
| SCHEMBL16458222 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315493-B2 | Phenylpyridine derivative and drug containing same | KOWA COMPANY, LTD. (JP) | 2016-04-19 | — | — | US | disclosed |
| EP-2687523-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA CO (JP) | 2016-01-06 | — | — | EP | disclosed |
| EP-2687523-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | Kowa Company Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140011823-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA COMPANY, LTD. (JP) | 2014-01-09 | — | — | US | disclosed |