SCHEMBL15423161

SCHEMBL15423161

CC1(C)c2cc(-c3ccccn3)cc3ccc4cc(-c5ccc(-c6ccncc6)cn5)cc1c4c23

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.41
PDGFRB P09619 4/20 0.40
PDGFRA P16234 4/20 0.40
PIK3CD O00329 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
PIK3CG P48736 1/20 0.38
MAPK9 P45984 2/20 0.37
MAPK10 P53779 2/20 0.37
MAPT P10636 2/20 0.37
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 2/20 0.36
PKM P14618 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
RAB9A P51151 1/20 0.36
WNT3A P56704 3/20 0.36
CYP2A6 P11509 1/20 0.36
ABL1 P00519 1/20 0.36
KDM4E B2RXH2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423171 0.90 TGFBR1 (0.42) TGFBR1PDGFRBPDGFRAPIK3CDPIK3CA
SCHEMBL15423208 0.85 KDM4E (0.39) PDGFRBPDGFRAMAPK9MAPK10MAPT
SCHEMBL15423191 0.84 NPC1 (0.45) PDGFRBPDGFRAPIK3CDPIK3CAPIK3CB
SCHEMBL15423188 0.82 PIM1 (0.39) MAPK10WNT3ACYP2A6ABL1
SCHEMBL15423165 0.82 CYP2A6 (0.43) TGFBR1MAPTNPC1ALDH1A1TP53
SCHEMBL15423169 0.80 SIRT2 (0.42) PIK3CDPIK3CAPIK3CBPIK3CGMAPK9
SCHEMBL15423177 0.80 SMN1; SMN2 (0.41) MAPTNPC1ALDH1A1TP53PKM
SCHEMBL15423172 0.80 ABL1 (0.42) PIK3CDPIK3CAPIK3CBPIK3CGMAPT
SCHEMBL16168904 0.79 CYP11B1 (0.41) MAPTNPC1ALDH1A1SMN1; SMN2RAB9A
SCHEMBL15423175 0.79 CYP2A6 (0.49) PDGFRBPDGFRANPC1TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed