SCHEMBL15423191

SCHEMBL15423191

CC1(C)c2cc(-c3ccc4ncccc4c3)cc3ccc4cc(-c5ccc(-c6cc(-c7ccncc7)cc(-c7ccncc7)c6)cn5)cc1c4c23

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
POLB P06746 1/20 0.45
PDGFRB P09619 5/20 0.43
PDGFRA P16234 5/20 0.43
DYRK1A Q13627 3/20 0.41
GAK O14976 1/20 0.39
CDK8 P49336 2/20 0.38
MAP4K4 O95819 1/20 0.38
CLK2 P49760 1/20 0.38
CDK7 P50613 1/20 0.38
CDK9 P50750 1/20 0.38
CDK5 Q00535 1/20 0.38
ACVR1 Q04771 1/20 0.38
ROCK1 Q13464 1/20 0.38
LRRK2 Q5S007 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
GRM1 Q13255 1/20 0.37
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423192 0.86 NPC1 (0.48) NPC1RAB9APOLBPDGFRBPDGFRA
SCHEMBL15423161 0.84 TGFBR1 (0.41) NPC1RAB9APDGFRBPDGFRACYP2A6
SCHEMBL15423208 0.84 KDM4E (0.39) NPC1RAB9APOLBPDGFRBPDGFRA
SCHEMBL15423168 0.83 NPC1 (0.55) NPC1RAB9APOLBDYRK1AKDM4E
SCHEMBL15423205 0.82 NPC1 (0.42) NPC1RAB9APOLBDYRK1ACDK8
SCHEMBL15423171 0.79 TGFBR1 (0.42) NPC1RAB9APOLBPDGFRBPDGFRA
SCHEMBL15423193 0.79 NPC1 (0.50) NPC1RAB9APOLBPDGFRBPDGFRA
SCHEMBL15423189 0.79 NPC1 (0.36) NPC1RAB9APOLBDYRK1ACDK7
SCHEMBL15423234 0.78 NPC1 (0.53) NPC1RAB9APOLBDYRK1AKDM4E
SCHEMBL15423188 0.77 PIM1 (0.39) DYRK1ACYP2A6ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed