SCHEMBL15423189

SCHEMBL15423189

CC1(C)c2cc(-c3ccc4ncccc4c3)cc3ccc4cc(-c5ccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)cn5)cc1c4c23

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
METAP2 P50579 1/20 0.35
GRM1 Q13255 1/20 0.35
PIK3CA P42336 6/20 0.35
MTOR P42345 5/20 0.35
PIK3CD O00329 4/20 0.35
DYRK1A Q13627 2/20 0.34
PIK3CB P42338 2/20 0.34
PIK3CG P48736 2/20 0.34
MAP3K8 P41279 1/20 0.34
PTGES O14684 1/20 0.34
GRK5 P34947 1/20 0.34
PIK3C2A O00443 2/20 0.33
PIK3C2B O00750 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16168898 0.82 METAP2 (0.35) NPC1POLBRAB9AMETAP2DYRK1A
SCHEMBL15423205 0.80 NPC1 (0.42) NPC1POLBRAB9AGRM1PIK3CA
SCHEMBL15423191 0.79 NPC1 (0.45) NPC1POLBRAB9AGRM1PIK3CA
SCHEMBL15423179 0.78 MAPT (0.41) NPC1POLBRAB9AMETAP2GRM1
SCHEMBL12731493 0.78 PIK3CA (0.33) PIK3CAMTORPIK3CDPIK3CBPIK3CG
SCHEMBL17998137 0.78 PIK3CA (0.43) NPC1POLBRAB9AMETAP2PIK3CA
SCHEMBL14305852 0.78 KDM4E (0.36) NPC1POLBRAB9AMETAP2MAP3K8
SCHEMBL12069852 0.77 PIK3CA (0.41) PIK3CAMTORPIK3CDPIK3CBPIK3CG
SCHEMBL15423168 0.77 NPC1 (0.55) NPC1POLBRAB9APIK3CAMTOR
SCHEMBL12731525 0.76 PDK2 (0.33) POLBMETAP2MTORMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed