SCHEMBL15423232

SCHEMBL15423232

CC1(C)c2cc(B3OC(C)(C)C(C)(C)O3)cc3ccc4cc(-c5ccccn5)cc1c4c23

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 6/20 0.45
LIPG Q9Y5X9 6/20 0.45
DGAT1 O75907 1/20 0.36
KDM4E B2RXH2 6/20 0.35
NPC1 O15118 3/20 0.35
TP53 P04637 4/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 3/20 0.34
PKM P14618 2/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
KLF5 Q13887 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP2A6 P11509 1/20 0.33
HPGD P15428 2/20 0.33
RAB9A P51151 2/20 0.33
PDE5A O76074 1/20 0.32
PDE1A P54750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15423231 0.83 LIPG (0.54) LPLLIPGDGAT1MAPTTSHR
SCHEMBL15423238 0.83 LPL (0.41) LPLLIPGDGAT1KDM4ENPC1
SCHEMBL19544227 0.83 LPL (0.47) LPLLIPGDGAT1KDM4ENPC1
SCHEMBL15423235 0.81 LPL (0.47) LPLLIPGKDM4ENPC1TP53
SCHEMBL17849690 0.81 LPL (0.46) LPLLIPGIRAK4
SCHEMBL22206079 0.79 LIPG (0.46) LPLLIPGDGAT1CYP2A6CYP1A2
SCHEMBL30322765 0.79 LIPG (0.46) LPLLIPGDGAT1CYP2A6CYP1A2
SCHEMBL15423233 0.78 KDM4E (0.39) KDM4ENPC1TP53SMN1; SMN2ALDH1A1
SCHEMBL9960104 0.78 LIPG (0.54) LPLLIPGDGAT1KDM4ENPC1
SCHEMBL23079973 0.77 CCR1 (0.49) LPLLIPGDGAT1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed