Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 5/20 | 0.61 |
| ▸ | MMP2 | P08253 | 4/20 | 0.60 |
| ▸ | MMP8 | P22894 | 4/20 | 0.60 |
| ▸ | MMP12 | P39900 | 4/20 | 0.60 |
| ▸ | MMP13 | P45452 | 4/20 | 0.60 |
| ▸ | MMP14 | P50281 | 4/20 | 0.60 |
| ▸ | MMP16 | P51512 | 4/20 | 0.60 |
| ▸ | MMP9 | P14780 | 3/20 | 0.60 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129486 | 1.00 | PKM (0.73) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL10672859 | 0.96 | HTT (0.73) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL12091354 | 0.95 | PKM (0.66) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL2900381 | 0.94 | PKM (0.83) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL18069681 | 0.92 | PKM (0.86) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL19008825 | 0.92 | PKM (0.86) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL17472319 | 0.92 | PKM (0.86) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL14148915 | 0.92 | PKM (0.86) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL17827515 | 0.91 | PKM (0.66) | PKMHTTSMN1; SMN2LTA4HGAA | |
| SCHEMBL6848913 | 0.90 | HTT (0.74) | PKMHTTSMN1; SMN2LTA4HPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550335-B1 | IMPROVED BLENDS OF POLYARYLENE ETHERS AND POLYARYLENE SULFIDES | BASF SE (DE) | 2014-01-15 | — | — | EP | disclosed |