SCHEMBL15426482

SCHEMBL15426482

CNc1ccc(C)nc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.37
CCR1 P32246 2/20 0.37
CCR5 P51681 1/20 0.37
EGFR P00533 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
LRRK2 Q5S007 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
CYP1A2 P05177 2/20 0.32
MAPK1 P28482 1/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15718645 0.79 SIRT2 (0.36) RAB9ASMN1; SMN2NPC1LRRK2ALDH1A1
SCHEMBL20684265 0.77 NR4A2 (0.45) RAB9ACCR1CCR5EGFRALDH1A1
SCHEMBL8307764 0.76 CCR1 (0.40) RAB9ACCR1CCR5ADORA2AADORA1
SCHEMBL6776759 0.74 NOS3 (0.39) RAB9ACCR1CCR5NPC1ALDH1A1
SCHEMBL25153150 0.73 APP (0.40) RAB9ACCR1CCR5NPC1CYP1A2
SCHEMBL16923586 0.73 KDM4E (0.38) RAB9ACCR1CCR5SMN1; SMN2NPC1
SCHEMBL18878176 0.73 CCR1 (0.37) RAB9ACCR1CCR5ALDH1A1MAPT
SCHEMBL28340018 0.72 ALDH1A1 (0.33) RAB9ACCR1CCR5EGFRSMN1; SMN2
SCHEMBL13044713 0.72 ESR1 (0.44) SMN1; SMN2ALDH1A1KDM4EMAPTCYP1A2
SCHEMBL17975144 0.72 DHODH (0.39) SMN1; SMN2KDM4EMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 RAB9A 694/4885CCR1 482/4885CCR5 2027/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 RAB9A 697/4885CCR1 498/4885CCR5 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.