Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427596 | 0.89 | KMT2A (0.59) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL15427597 | 0.83 | THRB (0.66) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL13719742 | 0.83 | NPC1 (0.74) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL3274053 | 0.81 | THRB (0.79) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL15427604 | 0.80 | NR1H4 (0.64) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL13027030 | 0.80 | NQO2 (0.41) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL6556053 | 0.80 | NQO2 (0.70) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL5604593 | 0.80 | KMT2A (0.69) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL13719791 | 0.79 | NPC1 (0.70) | LMNANPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL12218322 | 0.78 | SCN10A (0.65) | LMNANPC1RAB9ASMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633335-B2 | Retinoid prodrug compound | Research Founation Itsuu Laboratory (JP) | 2014-01-21 | — | — | US | disclosed |