SCHEMBL15428296

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15428304	0.94	MEN1 (0.42)	PTGER4KMT2AMEN1TDP1CYP1A2
	SCHEMBL15415885	0.91	PTGER4 (0.40)	PTGER4KMT2AMEN1TDP1CYP1A2
	SCHEMBL15416079	0.87	MEN1 (0.42)	PTGER4KMT2AMEN1TDP1CYP1A2
	SCHEMBL15416038	0.86	MEN1 (0.40)	KMT2AMEN1TDP1TBXA2RBACE1
	SCHEMBL15416463	0.85	MEN1 (0.41)	PTGER4KMT2AMEN1TDP1CYP1A2
	SCHEMBL15415359	0.83	—	—
	SCHEMBL15416116	0.80	KDM4C (0.39)	KMT2AMEN1CYP2D6TBXA2RCYP2C19
	SCHEMBL15416230	0.80	KMT2A (0.34)	KMT2AMEN1TBXA2R
	SCHEMBL15416695	0.79	AKR1B1 (0.35)	TDP1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL15428321	0.79	KMT2A (0.45)	KMT2ATBXA2RBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.