Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428858 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4ECE1 | |
| SCHEMBL3661088 | 0.83 | ECE1 (0.33) | ECE1 | |
| SCHEMBL3695948 | 0.82 | ECE1 (0.32) | ECE1 | |
| SCHEMBL3667412 | 0.80 | ECE1 (0.34) | ECE1 | |
| SCHEMBL3661960 | 0.80 | ECE1 (0.31) | ECE1 | |
| SCHEMBL3665726 | 0.79 | ECE1 (0.30) | ECE1 | |
| SCHEMBL2142444 | 0.78 | ECE1 (0.32) | ECE1 | |
| SCHEMBL5049589 | 0.78 | ECE1 (0.32) | ECE1 | |
| SCHEMBL3666706 | 0.77 | ECE1 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4ECE1 | |
| SCHEMBL3663065 | 0.77 | ALOX15 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346831-B1 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-8637550-B2 | Heteroaryl diamide compounds useful as MMP-13 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-28 | — | — | US | disclosed |