SCHEMBL15430283

SCHEMBL15430283

c1ccc(-c2ccc3c(c2)c2cc(-c4cccc(-c5cccc6c5sc5ccccc56)c4)ccc2n2ccnc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
PRKDC P78527 3/20 0.37
DNPH1 O43598 1/20 0.37
LIMK1 P53667 4/20 0.35
PARP14 Q460N5 1/20 0.33
PIM3 Q86V86 1/20 0.32
TACR1 P25103 1/20 0.32
ADK P55263 1/20 0.31
TDO2 P48775 1/20 0.31
MAP3K8 P41279 2/20 0.30
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
F9 P00740 1/20 0.30
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30
MAPK1 P28482 1/20 0.30
MAP2K1 Q02750 1/20 0.30
ROCK1 Q13464 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430222 0.96 ALOX5 (0.46) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15405596 0.95 ALOX5 (0.46) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15405088 0.95 ALOX5 (0.46) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430282 0.94 ALOX5 (0.41) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430225 0.94 ALOX5 (0.43) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430228 0.93 ALOX5 (0.46) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430220 0.92 ALOX5 (0.44) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430223 0.92 ALOX5 (0.44) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430226 0.91 ALOX5 (0.42) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL15430285 0.90 ALOX5 (0.39) ALOX5PRKDCDNPH1PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed