SCHEMBL15430299

SCHEMBL15430299

c1ccc(-c2cccc3c2oc2ccccc23)c(-c2ccc(-c3ccc4c(c3)c3ccccc3c3nccn43)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
PRKDC P78527 6/20 0.35
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
ADK P55263 1/20 0.34
GGPS1 O95749 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.32
ATM Q13315 1/20 0.32
DRD4 P21917 1/20 0.32
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30
CCNC P24863 1/20 0.30
CDK8 P49336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430297 0.96 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430303 0.96 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430307 0.96 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430296 0.96 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430301 0.95 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430302 0.94 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430304 0.92 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL23866422 0.91 ALOX5 (0.49) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430311 0.91 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBADK
SCHEMBL15430298 0.91 ALOX5 (0.46) ALOX5PRKDCPIK3CDPIK3CBADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed