SCHEMBL15430307

SCHEMBL15430307

c1ccc(-c2ccccc2-c2cccc3c2oc2ccccc23)c(-c2ccc3c(c2)c2ccccc2c2nccn32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
GGPS1 O95749 1/20 0.37
PRKDC P78527 6/20 0.37
PIK3CD O00329 1/20 0.35
PIK3CB P42338 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.35
ADK P55263 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
ATM Q13315 1/20 0.33
DRD4 P21917 1/20 0.33
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
MAPT P10636 2/20 0.30
NPC1 O15118 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
TACR1 P25103 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430296 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430301 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430299 0.96 ALOX5 (0.40) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL23866422 0.96 ALOX5 (0.49) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430311 0.95 ALOX5 (0.44) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430306 0.95 ALOX5 (0.46) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430305 0.93 ALOX5 (0.46) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430298 0.93 ALOX5 (0.46) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430304 0.92 ALOX5 (0.46) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15430303 0.91 ALOX5 (0.44) ALOX5GGPS1PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20070037979-A1 Preparation of rosuvastatin TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037979-A1 Preparation of rosuvastatin HMGCR, PCSK9, PCSK7 ALOX5 1278/4885GGPS1 8/4885PRKDC 2803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.