SCHEMBL15430345

SCHEMBL15430345

Cc1cccc2c1oc1c(-c3cccc(-c4ccc5c(c4)c4ccccc4c4nccn54)c3)cccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 11/20 0.36
CLK4 Q9HAZ1 3/20 0.34
FLT1 P17948 1/20 0.34
CDK8 P49336 1/20 0.34
CDK9 P50750 1/20 0.34
LIMK1 P53667 1/20 0.34
ROCK1 Q13464 1/20 0.34
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP2C19 P33261 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BRD4 O60885 1/20 0.31
TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430338 0.92 PRKDC (0.36) PRKDCCDK8ALOX5ALDH1A1CYP2C19
SCHEMBL15430298 0.88 ALOX5 (0.46) PRKDCALOX5
SCHEMBL15430305 0.88 ALOX5 (0.46) PRKDCALOX5
SCHEMBL15430337 0.87 PRKDC (0.32) PRKDC
SCHEMBL15430347 0.87 PRKDC (0.33) PRKDCALOX5TACR1
SCHEMBL15430304 0.87 ALOX5 (0.46) PRKDCALOX5
SCHEMBL15430306 0.85 ALOX5 (0.46) PRKDCALOX5TACR1
SCHEMBL15430366 0.85 ALOX5 (0.42) PRKDCCLK4FLT1CDK8CDK9
SCHEMBL15430302 0.84 ALOX5 (0.43) PRKDCALOX5
SCHEMBL23866422 0.84 ALOX5 (0.49) PRKDCALOX5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed