Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357917 | 0.81 | HDAC1 (0.46) | GAAALDH1A1KDM4EGLAHDAC1 | |
| Hydrochloric Acid SCHEMBL29373586 | 0.80 | HDAC1 (0.45) | GAAALDH1A1KDM4EGLAHDAC1 | |
| Hydrochloric Acid SCHEMBL5749683 | 0.80 | HDAC1 (0.45) | GAAALDH1A1KDM4EGLAHDAC1 | |
| SCHEMBL6988265 | 0.79 | CYP1A2 (0.41) | GAAALDH1A1KDM4EGLAHDAC1 | |
| SCHEMBL9425432 | 0.79 | ALDH1A1 (0.45) | GAAALDH1A1KDM4EAOC1AOC3 | |
| SCHEMBL18858121 | 0.78 | GAA (0.39) | GAAALDH1A1KDM4EGLAHDAC1 | |
| SCHEMBL6988259 | 0.78 | GAA (0.39) | GAAALDH1A1KDM4EGLAHDAC1 | |
| Hydrochloric Acid SCHEMBL9426022 | 0.78 | CYP1A2 (0.40) | GAAALDH1A1GLAHDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL9426498 | 0.77 | ALDH1A1 (0.44) | GAAALDH1A1KDM4EAOC1AOC3 | |
| SCHEMBL9017891 | 0.76 | HDAC1 (0.49) | GAAALDH1A1KDM4EGLAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140024621-A1 | AMINOPYRIDINE COMPOUNDS AND THEIR USES | MS THERAPEUTICS LIMITED (GB) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024621-A1 | AMINOPYRIDINE COMPOUNDS AND THEIR USES | DNPEP, PEPD, ANPEP | GAA 254/4885ALDH1A1 264/4885KDM4E 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.