SCHEMBL15433265

SCHEMBL15433265

C/C(F)=C(\F)c1ccc(CCc2cc(F)c(-c3cc(F)c(C(F)(F)F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.39
KIF11 P52732 2/20 0.33
S1PR1 P21453 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433259 0.89 KIF11 (0.42) DAOKIF11S1PR1
SCHEMBL15433575 0.85 DAO (0.34) DAOKIF11S1PR1
SCHEMBL15433310 0.84 KIF11 (0.39) DAOKIF11
SCHEMBL15433706 0.82 KIF11 (0.40) DAOKIF11S1PR1
SCHEMBL15433500 0.82 RARB (0.34) DAOKIF11S1PR1
SCHEMBL15433688 0.80 MAOB (0.33)
SCHEMBL15433433 0.79 KIF11 (0.42) KIF11
SCHEMBL15433304 0.79 DAO (0.36) DAOKIF11
SCHEMBL15433549 0.78 RARB (0.43) S1PR1
SCHEMBL15433294 0.77 MAOB (0.39) S1PR1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed