SCHEMBL15433500

SCHEMBL15433500

CCC/C(F)=C(\F)c1ccc(CCc2ccc(-c3cc(F)c(-c4cc(F)c(C(F)(F)F)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.34
RARA P10276 2/20 0.34
RARG P13631 1/20 0.34
KIF11 P52732 2/20 0.34
CNR2 P34972 2/20 0.32
S1PR1 P21453 1/20 0.32
MPL P40238 3/20 0.31
DAO P14920 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MTOR P42345 1/20 0.31
KMT2A Q03164 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433575 0.98 DAO (0.34) RARBRARARARGKIF11CNR2
SCHEMBL15433835 0.94 KIF11 (0.36) KIF11
SCHEMBL15433498 0.89 RARB (0.41) RARBRARARARGKIF11S1PR1
SCHEMBL15433497 0.85 KIF11 (0.38) RARBRARARARGKIF11S1PR1
SCHEMBL15433428 0.82 KIF11 (0.37) RARBKIF11MEN1ALDH1A1MAPT
SCHEMBL15433577 0.82 RARB (0.35) RARBRARARARGS1PR1DAO
SCHEMBL15433304 0.82 DAO (0.36) RARBRARARARGKIF11DAO
SCHEMBL15433265 0.82 DAO (0.39) KIF11S1PR1DAO
SCHEMBL15433211 0.81 KIF11 (0.38) RARBRARARARGKIF11
SCHEMBL15433259 0.81 KIF11 (0.42) RARBRARARARGKIF11S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed