SCHEMBL15433352

SCHEMBL15433352

CCC/C(F)=C(\F)c1ccc(-c2cc(F)c(C(F)(F)Oc3cc(F)c(OC(F)(F)F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433284 0.87 GSK3B (0.34) FFAR1FFAR4GSK3B
SCHEMBL15433799 0.85 ALOX5AP (0.32) FFAR1FFAR4
SCHEMBL15433816 0.83 S1PR1 (0.34) FFAR1FFAR4
SCHEMBL15433349 0.81 ANPEP (0.32)
SCHEMBL15433795 0.81 KIF11 (0.34) FFAR1FFAR4
SCHEMBL15433225 0.80 KIF11 (0.35) FFAR1FFAR4
SCHEMBL15744608 0.80 RARB (0.33) FFAR4
SCHEMBL15433631 0.80 GSK3B (0.36) FFAR1FFAR4GSK3B
SCHEMBL15433821 0.79 FFAR4 (0.33) FFAR4
SCHEMBL15433769 0.78 ANPEP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed