SCHEMBL15433795

SCHEMBL15433795

CCCCCC/C(F)=C(\F)c1ccc(-c2ccc(-c3ccc(C(F)(F)Oc4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.34
MGLL Q99685 13/20 0.33
FAAH O00519 2/20 0.32
CNR1 P21554 2/20 0.32
RARB P10826 2/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433350 0.89 KIF11 (0.37) KIF11MGLLFAAHCNR1RARB
SCHEMBL15433767 0.83 KIF11 (0.34) KIF11MGLLRARBRARA
SCHEMBL15433651 0.82 KIF11 (0.36) KIF11CYP11B1CYP11B2
SCHEMBL15433352 0.81 FFAR1 (0.31) FFAR1FFAR4
SCHEMBL15433796 0.81 KIF11 (0.32) KIF11
SCHEMBL15433798 0.80 KIF11 (0.31) KIF11
SCHEMBL15433800 0.79
SCHEMBL15433634 0.79 KIF11 (0.36) KIF11CYP11B1CYP11B2
SCHEMBL15433659 0.79 KIF11 (0.40) KIF11CYP11B1CYP11B2
SCHEMBL15433658 0.78 FFAR4 (0.33) KIF11CYP11B1CYP11B2FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed