Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661179 | 1.00 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL14496915 | 1.00 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2754791 | 0.92 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL234834 | 0.92 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10079082 | 0.90 | ACHE (0.51) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL15433373 | 0.90 | ACHE (0.51) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL15433370 | 0.89 | MPI (0.44) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL14823076 | 0.89 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL825843 | 0.88 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL12133421 | 0.88 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633307-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-01-21 | — | — | US | disclosed |