Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15433373 | 1.00 | ACHE (0.51) | ACHEHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL12133421 | 0.95 | MEN1 (0.48) | ACHEHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL17787274 | 0.92 | MEN1 (0.50) | ACHEHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL14496915 | 0.90 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL15433372 | 0.90 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL12661179 | 0.90 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL14823076 | 0.90 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL13644731 | 0.90 | MEN1 (0.43) | ACHEHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL11124573 | 0.89 | PTPN1 (0.41) | ACHEHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL11124572 | 0.89 | PTPN1 (0.41) | ACHEHSD17B10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466266-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-8119781-B2 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100130733-A1 | LUMINESCENT METAL ION COMPLEXES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-7635762-B2 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-12-22 | — | — | US | disclosed |
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES (US) | 2009-10-15 | — | — | US | disclosed |
| US-7582432-B2 | Multiplexing methods using dark quenchers, nonfluorescing disazo dyes, functionalized for their rapid attachment to probe components; engineered to have a desired light absorption profile; facilitate interaction between quencher and fluorophore without form nucleic acid secondary structure | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070154898-A1 | Multiplexing methods using dark quenchers, nonfluorescing disazo dyes, functionalized for their rapid attachment to probe components; engineered to have a desired light absorption profile; facilitate interaction between quencher and fluorophore without form nucleic acid secondary structure | BIOSEARCH TECHNOLOGIES, INC. (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | ACHE 3522/4885HSD17B10 4325/4885MEN1 3912/4885 |
| US-20100130733-A1 | LUMINESCENT METAL ION COMPLEXES | SLC30A6, SLC39A14, SLC39A3 | ACHE 2334/4885HSD17B10 3739/4885MEN1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.